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[What is Restless Legs (RLS) ?] [Medical Opinion] [Diagnosis]
[Remedies] [Remedies - Detail] [News]

Diagnosis
Essential features
Desire to move the limbs, usually associated with paresthesias/dysesthesias
Motor restlessness
Exacerbation of sensorimotor features by repose, relief with activity
Circadian variability, with the worst symptoms in the evening and early in the night
Additional features
Sleep disturbance, especially, difficulty in sleep initiation
Involuntary movements (periodic limb movements) that can occur during sleep or rest
Absence of associated abnormalities on neurological examination
Clinical course: severity of syndrome increases with advancing age; onset at any age with a typically chronic and progressive course; occasional remissions; frequent onset or aggravation during pregnancy; frequent exacerbation by caffeine
Suggestive family history consistent with dominant inheritance (but may only be elicited by direct interview of first and second degree relatives)
Clinical Assessment Questions
0 = none 1 = mild 2 = moderate 3=severe 4 = very severe
Using this scale, how would you rate the following symptoms?
Uncomfortable feelings in the legs and/or arms at rest in the evening or at night?
Need or urge to move around for relief when at rest in the evening or at night?
Uncontrollable jerks in your legs and/or arms that occur when you rest in the evening or at night?
Difficulty in getting to sleep when you first lie down to sleep?
Difficulty staying asleep during the night after you have first been asleep?
Sleepiness or fogginess during the daytime?
Leg discomfort
Leg cramps
Dysesthesias of peripheral neuropathy
Radiculopathy causing limb pain or discomfort
Delusions of infestation
Peripheral vascular insufficiency
Painful legs and moving toes
Motor restlessness or involuntary movements
Akathisia
Anxiety states
Tic disorders
Propriospinal myoclonus
Drug withdrawal
Manic or excitable states
Muscle twitches (fasciculations, myokymia, myoclonus)
Periodic limb movements of sleep
Excessive nocturnal movement - may be due to pain or medical condition or may be a separate
Hypnic jerks (sleep starts)
Nocturnal seizures
Nightmares or night terrors
Movements associated with sleep-related respiratory disorders
REM sleep behaviour disorder
Parasomnias (e.g., sleepwalking)
Rhythmic movement disorder (e.g., head banging)
Conditions Associated with RLS and PLMS
Physiologic conditions
Pregnancy
Aging
Medical conditions
Iron deficiency, with or without anemia
Uremia in renal failure
Diabetes
Gastrectomy
Cancer
Chronic obstructive pulmonary disease
Rheumatoid arthritis
Peripheral vascular disease
